Proteases secreted by Gnathostoma binucleatum degrade fibronectin and antibodies from mammals

Leptospira interrogans Secreted Proteases Degrade Extracellular Matrix and Plasma Proteins From the Host

Citation: da Silva LB, Menezes MC, Kitano ES, Oliveira AK, Abreu AG, Souza GO, Heinemann MB, Isaac L, Fraga TR, Serrano SMT and Barbosa AS (2018) Leptospira interrogans Secreted Proteases Degrade Extracellular Matrix and Plasma Proteins From the Host. Front. Cell. Infect. Microbiol. 8:92. doi: 10.3389/fcimb.2018.00092 Leptospira interrogans Secreted Proteases Degrade Extracellular Matrix and Pl...

Secreted proteases from Photorhabdus luminescens: separation of the extracellular proteases from the insecticidal Tc toxin complexes.

Photorhabdus luminescens secretes both high molecular weight insecticidal toxin complexes and also a range of extracellular proteases into culture broth. Previous studies by others have suggested that insecticidal activity of the broth is associated with these proteases. However, by gene cloning and targeted knock-out, we have previously shown that oral insecticidal activity is associated with ...

Interaction Studies of Secreted Aspartic Proteases (Saps) from Candida albicans

Focal cerebral ischemia induces active proteases that degrade microvascular matrix.

BACKGROUND AND PURPOSE Focal cerebral ischemia causes microvessel matrix degradation and generates proteases known to degrade this matrix. However, proof that the proteases generated do indeed degrade vascular matrix is lacking. Here we demonstrate that active proteases derived from ischemic tissue after middle cerebral artery occlusion (MCAO) and transferred to normal tissue can degrade vascul...

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin.

Gel-filtration chromatography of culture medium from rabbit bone explants separates three latent metalloproteinases with activities against collagen, proteoglycan and gelatin respectively. The fractions degrading proteoglycan also degrade laminin, fibronectin and the polymeric products of pepsin-solubilized type IV collagen and can also solubilize insoluble type IV collagen. The fractions degra...